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Collage of Research subjects

Fall Seminar

Speaker

Tim Yoshino, PhD

University of Wisconsin School of Medicine

When: Oct 27, 2017 - 12:00pm - 12:00pm

Where: TBA

Research Detail

Human schistosomiasis is a neglected tropical disease that results from infection by several species of the parasitic flatworm Schistosoma. My research is focused on defining and characterizing the molecular basis for innate resistance and susceptibility of inbred strains of the snail Biomphalaria glabratato infection by larvae of the human blood fluke Schistosoma mansoni, causative agent of hepatosplenic schistosomiasis. Methods involving cellular and molecular biology, tissue culture, genomics/proteomics and whole organism manipulations are used to define and characterize the innate immune system of the snail host, in order to gain a better understanding of the underlying processes regulating immune resistance to schistosome larval infection.